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1

Shanghai International Consensus on Diagnosis and Comprehensive Treatment of Colorectal Liver Metastases (Version 2019)

Ren, Li, Zhu, Dexiang, Benson, Al B., Nordlinger, Bernard, Koehne, Claus-Henning, Delaney, Conor P., Kerr, David, Lenz, Heinz-Josef, Fan, Jia, Wang, Jianping, Gu, Jin, Li, Jin, Shen, Lin, Tsarkov, Pet

Journal:

European Journal of Surgical Oncology (EJSO)

Année:

2020

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2020

2

Listening in on difficult conversations: an observational, multi-center investigation of real-time conversations in medical oncology

Kimball, Brittany C, James, Katherine M, Yost, Kathleen J, Fernandez, Cara A, Kumbamu, Ashok, Leppin, Aaron L, Robinson, Marguerite E, Geller, Gail, Roter, Debra L, Larson, Susan M, Lenz, Heinz-Josef,

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 254 KB

english, 2013

3

Cetuximab Plus Cisplatin, Irinotecan, and Thoracic Radiotherapy as Definitive Treatment for Locally Advanced, Unresectable Esophageal Cancer: A Phase-II Study of The SWOG (S0414)

Tomblyn, Michael B., Goldman, Bryan H., Thomas, Charles R., Benedetti, Jacqueline K., Lenz, Heinz-Josef, Mehta, Vivek, Beeker, Thaddeus, Gold, Philip J., Abbruzzese, James L., Blanke, Charles D.

Journal:

Journal of Thoracic Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 223 KB

english, 2012

4

A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma

El-Khoueiry, Anthony B., O’Donnell, Robert, Semrad, Thomas J., Mack, Philip, Blanchard, Suzette, Bahary, Nathan, Jiang, Yixing, Yen, Yun, Wright, John, Chen, Helen, Lenz, Heinz-Josef, Gandara, David R

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 604 KB

english, 2018

5

Association of Coffee Intake With Survival in Patients With Advanced or Metastatic Colorectal Cancer

Mackintosh, Christopher, Yuan, Chen, Ou, Fang-Shu, Zhang, Sui, Niedzwiecki, Donna, Chang, I-Wen, OâNeil, Bert H., Mullen, Brian C., Lenz, Heinz-Josef, Blanke, Charles D., Venook, Alan P., Mayer, Rob

Journal:

Année:

2020

Fichier:

PDF, 437 KB

2020

6

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines

Melissa J LaBonte, Peter M Wilson, William Fazzone, Susan Groshen, Heinz-Josef Lenz, Robert D Ladner

Journal:

BMC Medical Genomics

Année:

2009

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2009

7

Understanding the FOLFOXIRI-regimen to optimize treatment for metastatic colorectal cancer

Sunakawa, Yu, Schirripa, Marta, Lenz, Heinz-Josef

Journal:

Critical Reviews in Oncology/Hematology

Année:

2016

Langue:

english

Fichier:

PDF, 701 KB

english, 2016

8

First-in-human phase I dose escalation study of MK-8033 in patients with advanced solid tumors

Keedy, Vicki L., Lenz, Heinz-Josef, Saltz, Leonard, Whisenant, Jennifer G., Berlin, Jordan D., Camacho, Luis H.

Journal:

Investigational New Drugs

Année:

2018

Langue:

english

Fichier:

PDF, 651 KB

english, 2018

9

Partition: a surjective mapping approach for dimensionality reduction

Millstein, Joshua, Battaglin, Francesca, Barrett, Malcolm, Cao, Shu, Zhang, Wu, Stintzing, Sebastian, Heinemann, Volker, Lenz, Heinz-Josef, Schwartz, Russell

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 417 KB

english, 2019

10

Molecular determinants of irinotecan efficacy

Daniel Vallböhmer, Syma Iqbal, Dong Yun Yang, Katrin E. Rhodes, Wu Zhang, Michael Gordon, William Fazzone, Anne M. Schultheis, Andy E. Sherrod, Kathleen D. Danenberg, Heinz-Josef Lenz

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 254 KB

english, 2006

11

Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells

William Fazzone, Peter M. Wilson, Melissa J. LaBonte, Heinz-Josef Lenz, Robert D. Ladner

Journal:

International Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 532 KB

english, 2009

12

The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38

Melissa J. LaBonte, Philipp C. Manegold, Peter M. Wilson, Will Fazzone, Stan G. Louie, Heinz-Josef Lenz, Robert D. Ladner

Journal:

International Journal of Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 482 KB

english, 2009

13

Interleukin-8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models

Yan Ning, Philipp C. Manegold, Young Kwon Hong, Wu Zhang, Alexandra Pohl, Georg Lurje, Thomas Winder, Dongyun Yang, Melissa J. LaBonte, Peter M. Wilson, Robert D. Ladner, Heinz-Josef Lenz

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2011

14

Germline polymorphisms in genes involved in the CD44 signaling pathway are associated with clinical outcome in localized gastric adenocarcinoma

Thomas Winder, Yan Ning, Dongyun Yang, Wu Zhang, Derek G Power, Pierre Bohanes, Armin Gerger, Peter M. Wilson, Georg Lurje, Laura H Tang, Manish Shah, Heinz-Josef Lenz

Journal:

International Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 366 KB

english, 2011

15

Quantification of chemotherapeutic target gene mRNA expression in human breast cancer biopsies: Comparison of real-time reverse transcription-PCR vs. Relative quantification reverse transcription-PCR utilizing DNA sequencer analysis of PCR products

Agnes Juhasz, Paul Frankel, Catherine Cheng, Hector Rivera, Reena Vishwanath, Alice Chiu, Kim Margolin, Yun Yen, Edward M. Newman, Tim Synold, Sharon Wilczynski, Heinz-Josef Lenz, David Gandara, Kathy

Journal:

Journal of Clinical Laboratory Analysis

Année:

2003

Langue:

english

Fichier:

PDF, 196 KB

english, 2003

16

Familial Adenomatous Polyposis (FAP) in 9 Hispanic women

Charite Ricker, Glenn Ault, Anthony El-Khoureiy, Syma Iqbal, Darcy Spicer, Heinz-Josef Lenz

Journal:

Hereditary Cancer in Clinical Practice

Année:

2010

Langue:

english

Fichier:

PDF, 169 KB

english, 2010

17

Characteristics of Lynch syndrome in 13 Hispanic Families

Charite Ricker, Nancy Klipfel, Glenn Ault, Lynda Roman, Darcy Spicer, Heinz-Josef Lenz

Journal:

Hereditary Cancer in Clinical Practice

Année:

2010

Langue:

english

Fichier:

PDF, 170 KB

english, 2010

18

Clinical trial of natural human lymphocyte-derived interleukin 2 in cancer patients: Effects on cytokine production and suppressor cell status

Graham Pawelec, Heinz-Josef Lenz, Edwin Schneider, Hans-Jörg Bühring, Arnika Rehbein, Petra Baumgärtner, Gerhard Ehninger

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 905 KB

english, 1991

19

Integration of novel agents in the treatment of colorectal cancer

Syma Iqbal, Heinz-Josef Lenz

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 210 KB

english, 2004

20

Phase I clinical and pharmacokinetic trial of docetaxel and irinotecan administered on a weekly schedule

Agustin A. Garcia, Mahesh Pujari, Susan Jeffers, Syma Iqbal, Heinz-Josef Lenz, Paul Beringer, Stan Louie

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 241 KB

english, 2005

21

A phase I study of oxaliplatin in combination with gemcitabine: correlation of clinical outcome with gene expression

Stephen Shibata, Warren Chow, Paul Frankel, Agnes Juhasz, Lucille Leong, Dean Lim, Kim Margolin, Robert Morgan, Edward Newman, George Somlo, Yun Yen, Timothy Synold, David Gandara, Heinz-Josef Lenz, J

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 386 KB

english, 2007

22

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU)

Jan H. Beumer, Robert A. Parise, Edward M. Newman, James H. Doroshow, Timothy W. Synold, Heinz-Josef Lenz, Merrill J. Egorin

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 321 KB

english, 2008

23

A phase II study of lapatinib in patients with advanced biliary tree and hepatocellular cancer

Ramesh K. Ramanathan, Chandra P. Belani, Deepti A. Singh, Michael Tanaka, Heinz-Josef Lenz, Yun Yen, Hedy L. Kindler, Syma Iqbal, Jeff Longmate, Philip C. Mack, Georg Lurje, Regina Gandour-Edwards, Ja

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 317 KB

english, 2009

24

Phase I trial of GTI-2040, oxaliplatin, and capecitabine in the treatment of advanced metastatic solid tumors: a California Cancer Consortium Study

Stephen I. Shibata, James H. Doroshow, Paul Frankel, Timothy W. Synold, Yun Yen, David R. Gandara, Heinz-Josef Lenz, Warren A. Chow, Lucille A. Leong, Dean Lim, Kim A. Margolin, Robert J. Morgan, Geor

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2009

Langue:

english

Fichier:

PDF, 310 KB

english, 2009

25

Dose-escalating and pharmacological study of bortezomib in adult cancer patients with impaired renal function: a National Cancer Institute Organ Dysfunction Working Group Study

Ticiana B. Leal, Scot C. Remick, Chris H. Takimoto, Ramesh K. Ramanathan, Angela Davies, Merrill J. Egorin, Anne Hamilton, Patricia A. LoRusso, Stephen Shibata, Heinz-Josef Lenz, James Mier, John Sara

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 397 KB

english, 2011

26

A phase II trial of gemcitabine and capecitabine in patients with unresectable or metastatic gallbladder cancer or cholangiocarcinoma: Southwest Oncology Group study S0202

Syma Iqbal, Cathryn Rankin, Heinz-Josef Lenz, Philip J. Gold, Syed A. Ahmad, Anthony B. El-Khoueiry, Michael J. Messino, Randall F. Holcombe, Charles D. Blanke

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 243 KB

english, 2011

27

A phase I and pharmacokinetic study of oral 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in the treatment of advanced-stage solid cancers: a California Cancer Consortium Study

Joseph Chao, Timothy W. Synold, Robert J. Morgan, Charles Kunos, Jeff Longmate, Heinz-Josef Lenz, Dean Lim, Stephen Shibata, Vincent Chung, Ronald G. Stoller, Chandra P. Belani, David R. Gandara, Mark

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 259 KB

english, 2012

28

Thymidylate synthase gene polymorphism predicts response to capecitabine in advanced colorectal cancer

David J. Park, Jan Stoehlmacher, Wu Zhang, Denice Tsao-Wei, Susan Groshen, Heinz-Josef Lenz

Journal:

International Journal of Colorectal Disease

Année:

2002

Langue:

english

Fichier:

PDF, 35 KB

english, 2002

29

Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: A Southwest Oncology Group study

Robert P. Whitehead, Sheryl McCoy, John S. Macdonald, Saul E. Rivkin, Marcus A. Neubauer, Shaker R. Dakhil, Heinz-Josef Lenz, Michael S. Tanaka, James L. Abbruzzese

Journal:

Investigational New Drugs

Année:

2006

Langue:

english

Fichier:

PDF, 376 KB

english, 2006

30

Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: a California cancer consortium study

Robert J. Morgan, Lucille Leong, Warren Chow, David Gandara, Paul Frankel, Agustin Garcia, Heinz-Josef Lenz, James H. Doroshow

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 117 KB

english, 2012

31

Can we predict the response to epidermal growth factor receptor targeted therapy?

Philipp C. Manegold, Georg Lurje, Alexandra Pohl, Yan Ning, Wu Zhang, Heinz-Josef Lenz

Journal:

Targeted Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 328 KB

english, 2008

32

Individualized chemotherapy based on genetic and genomic profiling

Syma Iqbal, Heinz-Josef Lenz

Journal:

Current Colorectal Cancer Reports

Année:

2005

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2005

33

Individualization of therapy based on clinical and molecular parameters

Georg Lurje, Alexandra Pohl, Phillip C. Manegold, Heinz-Josef Lenz

Journal:

Current Colorectal Cancer Reports

Année:

2008

Langue:

english

Fichier:

PDF, 282 KB

english, 2008

34

Using The Colon Cancer Multigene Recurrence Score to Determine Risk: Prognostic Milestone or a Step in the Right Direction?

Peter M. Wilson, Pierre Bohanes, Heinz-Josef Lenz

Journal:

Current Colorectal Cancer Reports

Année:

2010

Langue:

english

Fichier:

PDF, 186 KB

english, 2010

35

Molecular predictors of treatment and outcome in colorectal cancer

Syma Iqbal, Heinz-Josef Lenz

Journal:

Current Gastroenterology Reports

Année:

2003

Langue:

english

Fichier:

PDF, 223 KB

english, 2003

36

Determinants of prognosis and response to therapy in colorectal cancer

Syma Iqbal, Heinz-Josef Lenz

Journal:

Current Oncology Reports

Année:

2001

Langue:

english

Fichier:

PDF, 323 KB

english, 2001

37

Mutant DNA in Plasma of Lung Cancer Patients: Potential for Monitoring Response to Therapy

TATSUO KIMURA, WILL S. HOLLAND, TOMOYA KAWAGUCHI, STEPHEN K. WILLIAMSON, KARI CHANSKY, JOHN J. CROWLEY, JAMES H. DOROSHOW, HEINZ-JOSEF LENZ, DAVID R. GANDARA, PAUL H. GUMERLOCK

Journal:

Annals of the New York Academy of Sciences

Année:

2004

Fichier:

PDF, 782 KB

2004

38

A phase II study of high-dose 24 hour continuous infusion 5-FU and leucovorin and low-dose PALA for patients with advanced pancreatic adenocarcinoma: A Southwest Oncology Group Study

Robert P. Whitehead, Jacqueline K. Benedetti, James L. Abbruzzese, Bach Ardalan, J. Wendall Goodwin, Stanley P. Balcerzak, Wolfram E. Samlowski, Heinz-Josef Lenz, John S. Macdonald

Journal:

Investigational New Drugs

Année:

2004

Langue:

english

Fichier:

PDF, 71 KB

english, 2004

39

Phase II clinical trial of 5-fluorouracil, trimetrexate, and leucovorin (NFL) in patients with advanced pancreatic cancer

Agustin A. Garcia, Lawrence Leichman, Joaquina Baranda, Lalita Pandit, Heinz-Josef Lenz, Cynthia G. Leichman

Journal:

Journal of Gastrointestinal Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 86 KB

english, 2003

40

Targeting IL-8 in colorectal cancer

Ning, Yan, Lenz, Heinz-Josef

Journal:

Expert Opinion on Therapeutic Targets

Année:

2012

Langue:

english

Fichier:

PDF, 290 KB

english, 2012

41

Messenger RNA Expression of Vascular Endothelial Growth Factor and Its Receptors in Primary Colorectal Cancer and Corresponding Liver Metastasis

Hirotoshi Kobayashi, Kenichi Sugihara, Hiroyuki Uetake, Tetsuro Higuchi, Masamichi Yasuno, Masayuki Enomoto, Hidekazu Kuramochi, Heinz-Josef Lenz, Kathleen D. Danenberg, Peter V. Danenberg

Journal:

Annals of Surgical Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 245 KB

english, 2008

42

LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome

Justin Stebbing, Aleksandra Filipovic, Ian O. Ellis, Andrew R. Green, Tanya Rapoz D’Silva, Heinz-Josef Lenz, R. Charles Coombes, Tingting Wang, Soo-Chin Lee, Georgios Giamas

Journal:

Breast Cancer Research and Treatment

Année:

2012

Langue:

english

Fichier:

PDF, 445 KB

english, 2012

43

A phase II randomized study of cetuximab and bevacizumab alone or in combination with gemcitabine as first-line therapy for metastatic pancreatic adenocarcinoma

Andrew H. Ko, Hagop Youssoufian, Jayne Gurtler, Karel Dicke, Omar Kayaleh, Heinz-Josef Lenz, Mark Keaton, Terry Katz, Shaila Ballal, Eric K. Rowinsky

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 177 KB

english, 2012

44

SWOG 0514: a phase II study of sorafenib in patients with unresectable or metastatic gallbladder carcinoma and cholangiocarcinoma

Anthony B. El-Khoueiry, Cathryn J. Rankin, Edgar Ben-Josef, Heinz-Josef Lenz, Philip J. Gold, R. Darryl Hamilton, Rangaswamy Govindarajan, Cathy Eng, Charles D. Blanke

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 198 KB

english, 2012

45

Quantitative determination of the ratio of mutated to normal ras genes in the blood of leukemia patients by allele-specific PCR

Tetsuro Horikoshi, Heinz-Josef Lenz, Kathleen Danenberg, Olaf M. Koch, Joseph R. Bertino, Peter V. Danenberg

Journal:

Leukemia Research

Année:

1994

Langue:

english

Fichier:

PDF, 1.51 MB

english, 1994

46

Pharmacogenomics and -genetics in colorectal cancer

Alexandra Pohl, Georg Lurje, Philipp C. Manegold, Heinz-Josef Lenz

Journal:

Advanced Drug Delivery Reviews

Année:

2009

Langue:

english

Fichier:

PDF, 192 KB

english, 2009

47

Phase II clinical trial of capecitabine in ovarian carcinoma recurrent 6–12 months after completion of primary chemotherapy, with exploratory TS, DPD, and TP correlates: a Gynecologic Oncology Group study

Agustin A. Garcia, John A. Blessing, Heinz-Josef Lenz, Kathleen M. Darcy, Robert S. Mannel, David Scott Miller, Nader Husseinzadeh

Journal:

Gynecologic Oncology

Année:

2005

Langue:

english

Fichier:

PDF, 132 KB

english, 2005

48

Cyclooxygenase-2 inhibitors in colorectal cancer

Jan Stoehlmacher, Heinz-Josef Lenz

Journal:

Seminars in Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 81 KB

english, 2003

49

Sensitive and reproducible quantitation of mucosal HIV-1 RNA and DNA viral burden in patients with detectable and undetectable plasma viral HIV-1 RNA using endoscopic biopsies

Pete A Anton, Michael A Poles, Julie Elliott, S.H Mao, Ian McGowan, Heinz-Josef Lenz, Irvin S.Y Chen

Journal:

Journal of Virological Methods

Année:

2001

Langue:

english

Fichier:

PDF, 812 KB

english, 2001

50

Introduction

Heinz-Josef Lenz

Journal:

Seminars in Oncology

Année:

2004

Langue:

english

Fichier:

PDF, 57 KB

english, 2004